Contact

  • Title: 教授(Professor)
  • Department: 細胞研究所(Cell Biology Lab)
  • Address:
  • Tel: 0931 8914291
  • Fax:
  • Email: gqguo@lzu.edu.cn
  • Homepage:
Bio

2003- :蘭州大學,教授,博士生導師;
1996-2003:蘭州大學,副教授;
1990-1992:植物分子遺傳國家重點實驗室,客座,開放課題項目負責人;
1987-1996:山東大學,助教、講師。

Professor, Lanzhou University, 2003-.
Associated Professor, Lanzhou University, 1996-2003.
Assistant Professor, Lecturer, Shandong University, 1987-1996.
Visiting scholar, State Key Laboratory of Plant Molecular Genetics, 1990-1992.

Academic Appointments

2000:蘭州大學,博士;
1995-1996:德國馬普研究所(科?。?,歐盟瑪麗.居里獎學金;
1987:蘭州大學細胞生物學專業,碩士;
1984:蘭州大學生物系,學士。

Ph.D. Lanzhou University, 2000.
Marie Curie scholarship, Max-Planck institute, Germany, 1995-1996.
M.S. Lanzhou University, 1987.
B.S. Lanzhou University, 1984.

 

Administrative Appointments

現任:

2012:《西北植物學報》編委

曾任:

蘭州大學細胞生物學研究所副所長(2004年以前)和所長(2012-2019)

國家自然科學基金委員會-生命科學部學科評議組會議專家(2014)

中國植物學會植物細胞生物學專業委員會委員(1998-2003)

Honors & Awards
Funding

    先后主持國家自然科學基金面上、重大研究計劃和重點項目,以及973項目子課題。目前主持2項國家自然基金在研項目:

    (1)CKRC3在維持擬南芥內源生長素穩態中的作用和機理;

    (2)組蛋白H2B單泛素化修飾對植物內源生長素穩態的影響和作用機理。

    生長素和細胞分裂素是調控植物生長發育的重要激素,對它們作用機理的研究一直是國際上的熱點。

    研究成果:(1)是國際上獨立發現生長素生物合成IPA途徑突變體taa1的4家實驗室之一,并進一步獨立提出了細胞分裂素通過促進生長素合成并抑制其極性運輸的作用機理調控植物發育[Plant J 66, 516–527 (2011)];(2)2004年提出胞間橋/通道功能假說[J Theor Biol 229: 139-146 (2004)],在國際上受到關注,被《Cell》、《PNAS》、《Trends Mol Med》、《Biol Rev》、《Cold Spring Harb Perspect Biol》和《Dev Biol》及相關專著所引用;(3)1990年在國際上公認為難度極大的小麥原生質體培養中首先實現再生細胞直接形成體細胞胚和再生植株 [科學通報(中文和英文版1990),中國科學(中文版1990,英文版1991)]。

Publications

部分發表論文(按年份順序排列)

  • 郭光沁、夏光敏、李忠誼、陳惠民,1990,小麥原生質體培養體細胞胚直接發生再生植株。科學通報 35(6): 480.
  • Guo GQ, Xia GM, Li ZY, Chen HM, 1990, Direct somatic embryogenesis and plant regeneration in protoplast culture of wheat.  Chin Sci B (Sci Bull) 35(17): 1495-6.
  • 郭光沁、夏光敏、李忠誼、陳惠民,1990,小麥原生質體再生細胞直接形成體細胞胚和再生植株。中國科學B 20(9): 970-4。
  • Guo GQ, Xia GM, Li ZY, Chen HM, 1991, Direct somatic embryogenesis and plant regeneration from protoplast-derived cells of wheat. Sci in China (ser B) 34(4): 438-45.
  • 郭光沁、許智宏、衛志明、陳惠民,1993,用PEG法向小麥原生質體導入外源基因獲得轉基因植株。科學通報 38(13): 1227-31。
  • Guo GQ, Xu ZH, Wei ZM, Chen HM, 1993, Trangenic plants obtained from wheat protoplasts transformed by PEG-mediated direct gene transfer. Chin Sci B (Sci Bull) 38(24): 2072-8.
  • Guo GQ, Maiwald F, Lorenzen P & Steinbiss HH, 1998, Factors influencing T-DNA transfer into wheat and barley cells by Agrobacterium tumefaciens. Cereal Res Comm 26: 15-22.
  • 李衛、郭光沁*(聯系人)、鄭國锠,2000,根癌農桿菌介導遺傳轉化研究的若干新進展。科學通報 45(8): 798-807。
  • Li W, Guo GQ*(聯系人), Zheng GC, 2000, Agrobacterium-mediated transformation: state of the art and future prospect. Chin Sci B (Sci Bull) 45(17): 1537-46.
  • Guo GQ*, Zheng GC, 2004, Hypotheses for the functions of intercellular bridges in male germ cell development and its cellular mechanisms. J Theor Biol 229: 139-146.
  • Wang QF, Li W, Yang Hai, Liu YL, Cao HH, Dornmayr-Pfaffenhuemer M, Stan-Lotter H, Guo GQ*, 2007, Halococcus qingdaonensis sp. nov., a halophilic archaeon isolated from a crude sea-salt sample. Int J Syst Evol Microbiol 57: 600-604.
  • Liu Y, Yan Z, Chen N, Di X, Huang J, Guo G*. 2010. Development and function of central cell in angiosperm female gametophyte. Genesis (Dev Genet) 48: 466-478.
  • Zhou ZY, Zhang CG, Wu L, Zhang CG, Chai J, Wang M, Jha A, Jia PF, Cui SJ, Yang M, Chen R, Guo GQ*. 2011. Functional characterization of the CKRC1/TAA1 gene and dissection of hormonal actions in the Arabidopsis root. Plant J 66: 516–527.
  • Wang L, Sun C, Wang ZH, Guo GQ*(聯系人). 2012. Mechanism of apoptotosis induced by ortho-topolin riboside in human hepatoma cell line SMMC-7721. Food Chem Toxico 50, 1962-1968.
  • Wu L, Pan L, Di DW, Wang L, Wang M, Lu CK, Wei SD, Zhang L, Zhang TZ, Amakorová P, Mrvková M, Novák O, Guo GQ*. 2015. Forward genetic screen for auxin-deficient mutants by cytokinin. Sci Rep 5, 11923; doi: 10.1038/srep11923.
  • Wu L, Zhou ZY, Zhang CG, Chai J, Zhou Q, Wang L, Hirnerová E, Mrvková M, Novák O, Guo GQ*. 2015. Functional roles of three cutin biosynthetic acyltransferases in cytokinin responses and skotomorphogenesis. PLoS One 10(3): e0121943; doi: 10.1371/journal.pone.0121943.
  • Di DW, Zhang C, Luo P, An CW, Guo GQ. 2015. The biosynthesis of auxin: How many paths truly lead to IAA? Plant Growth Regulation 78, 275-285.
  • Di DW, Zhang C, Guo GQ. 2015. Involvement of secondary messengers and small organic molecules in auxin perception and signaling. Plant Cell Rep 34(6):895-904.
  • Zhao L, Liu P, Guo G*, Wang L*. 2015. Combination of cytokinin and auxin induces apoptosis, cell cycle progression arrest and blockage of the Akt pathway in HeLa cells. Mol Med Rep 12: 719-727.
  • Di DW, Wu L, Zhang L, An CW, Zhang TZ, Luo P, Gao HH, Kriechbaumer V, Guo GQ*. 2016. Functional roles of Arabidopsis CKRC2/YUCCA8 gene and the involvement of PIF4 in the regulation of auxin biosynthesis by cytokinin. Sci Rep 6, 36866; doi: 10.1038/srep36866.
  • Zhou Y, Zhang J, Lin H, Guo GQ, Guo Y. 2010. MORPHEUS’ MOLECULE1 is required to prevent aberrant RNA transcriptional read-through in Arabidopsis. Plant Physiol 154: 1272–1280.
  • Zhang CG, Guo HH, Zhang J, Guo GQ, Schumaker K, Guo Y. 2010. Arabidopsis CSAat1A and CSAat1B proteins form a complex with CULLIN4 and DDB1A and regulate the response to UV irradiation. Plant Cell 22: 2353-2369.
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